pksS
168
cytochrome P450, hydroxylase of the polyketide bacillaene produced by the pks cluster
locus
BSU_17230
Molecular weight
43.26 kDa
pI
6.12
function
polyketide synthesis
product
hydroxylase of the polyketide produced by the pks cluster
essential
no
synonyms
pksS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2124 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,858,566 → 1,859,783
The protein
Catalyzed reaction/ biological activity
hydroxylation of dihydrobacillaene [Pubmed|17482575]
Protein family
[wiki|cytochrome P450] family (according to UniProt)
Structure
[PDB|4YZR]
[AF|O31785]
Paralogous protein(s)
[protein|A95C28DEE73AD25E28C45B88A7C03C92835F9705|cypA], [protein|8FBC9A1AC108DC99E275D7A27C18C797D3CDB936|bioI], [protein|D8E72C2523D5E6214C9CBAC2C1B27EA45378E162|yjiB]
Expression and Regulation
Operons
genes
[gene|EF0F13BB682791E167EFC350BF029B08E8A1F410|pksS]
description
[Pubmed|22383849]
Biological materials
Mutant
BKE17230 (Δ[gene|EF0F13BB682791E167EFC350BF029B08E8A1F410|pksS]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCATTCTCCTCGCCT, downstream forward: _UP4_TAACATTCAAAACGCCCCCT
BKK17230 (Δ[gene|EF0F13BB682791E167EFC350BF029B08E8A1F410|pksS]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCATTCTCCTCGCCT, downstream forward: _UP4_TAACATTCAAAACGCCCCCT
References
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Time of last update: 2024-12-06 17:27:47
Author of last update: Melvin.boenninger