ytpR
168
similar to Phe-tRNA synthetase (beta subunit)
locus
BSU_29820
Molecular weight
21.55 kDa
pI
4.27
function
unknown
product
unknown
essential
no
synonyms
ytpR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0073 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,052,743 → 3,053,348
The protein
[wiki|Domains]
[wiki|tRNA-binding domain] (aa 90-200) (accordinig to UniProt)
Structure
[PDB|3BU2] (tRNA-binding protein from Staphylococcus saprophyticus, 59% identity)
[AF|O34943]
Expression and Regulation
Operons
genes
[gene|314D5C01B4BDDC3B122F6D4066647B143B2A6543|ytpP]-[gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]-[gene|EE559CD606562097F09DC627F431CA31129D7BC6|ytpR]
description
[Pubmed|21949854]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [Pubmed|21949854], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21949854], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-A512 (ytpR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/512 NBRP B. subtilis, Japan]
BKE29820 (Δ[gene|EE559CD606562097F09DC627F431CA31129D7BC6|ytpR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGCGTTCATAAGTAAAAATC, downstream forward: _UP4_TAGACTCCCATAAATCCGCC
BKK29820 (Δ[gene|EE559CD606562097F09DC627F431CA31129D7BC6|ytpR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGCGTTCATAAGTAAAAATC, downstream forward: _UP4_TAGACTCCCATAAATCCGCC
References
Reviews
Original Publications
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Time of last update: 2024-12-29 21:55:43
Author of last update: Jstuelk