dppC
168
dipeptide [protein|search|ABC transporter] (permease)
locus
BSU_12940
Molecular weight
35.65 kDa
pI
9.81
function
uptake of dipeptides
product
dipeptide [wiki|ABC transporter] (permease)
essential
no
synonyms
dppC, dciAC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1173 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,362,174 → 1,363,136
The protein
Protein family
[wiki|Binding-protein-dependent transport system permease family] (according to UniProt)
[wiki|OppBC subfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transmembrane type-1 domain] (aa 117-307) (according to UniProt)
Structure
[AF|P26904]
Paralogous protein(s)
[protein|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC], [protein|DDBCE73B6AF39E5D669475479186C93F287DA9FC|oppC]
[wiki|Localization]
cell membrane [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]-[gene|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]-[gene|7FA72D949B930A3C7FF0391CC6CCC58EEFCA839A|dppD]-[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]
description
[Pubmed|1766371]
regulation
repressed by glucose (2.9-fold) [Pubmed|12850135]
regulatory mechanism
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY]: repression, [Pubmed|7783641], in [regulon|protein:90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|1766371], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]-[gene|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]-[gene|7FA72D949B930A3C7FF0391CC6CCC58EEFCA839A|dppD]-[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]-[gene|C4F85F85F0C99A59145961E34B19D3AD03D2BC22|ykfA]-[gene|77EFC47449D8CC17651ED61C41AC605FCEF01270|ykfB]-[gene|D40ECAE51D9E4791C6FAAA25E2E0D0591D9FAA55|ykfC]-[gene|BB94F5388A0D1FF025E5A88A7E10AE7E4C489E5F|ykfD]
description
[pubmed|22383849]
regulatory mechanism
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY]: repression, [Pubmed|12618455], in [regulon|protein:90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY regulon]
Biological materials
Mutant
BKE12940 (Δ[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE12940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGTACAGGGAGATTCACAC, downstream forward: _UP4_GACCCTAAGCTGAGGAGGTA
BKK12940 (Δ[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK12940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGTACAGGGAGATTCACAC, downstream forward: _UP4_GACCCTAAGCTGAGGAGGTA
References
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Time of last update: 2024-12-21 12:54:48
Author of last update: Jstuelk