fpbO
168
petrobactin (3.4-catecholate siderophore) [wiki|ABC transporter] (permease)
locus
BSU_03810
Molecular weight
35.32 kDa
pI
9.73
function
acquisition of iron
product
petrobactin [wiki|ABC transporter] (permease)
essential
no
synonyms
fpbO, yclO
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4605 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
433,315 → 434,262
The protein
Catalyzed reaction/ biological activity
uptake of the siderophore petrobactin [Pubmed|19955416]
Protein family
[wiki|Binding-protein-dependent transport system permease family] (according to UniProt)
[wiki|FecCD subfamily] (according to UniProt)
Structure
[AF|P94419]
[wiki|Localization]
cell membrane [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|552D4C42DCEA4625000160D2625711C61AB11661|fpbN]-[gene|EC63B5CDFDB4DF3A967ECEC40F2C44849311148B|fpbO]-[gene|473628F86C18FE9957841F3C8B45242C90CB341D|fpbP]-[gene|C1D6D188E5BD039F32427B2A58BBFC0CC173A476|fpbQ]
description
[Pubmed|19955416]
regulation
immediately induced upon iron starvation (first wave to allow iron uptake) ([protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]) [Pubmed|29133393,12354229]
regulatory mechanism
[protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]: repression, [pubmed|12354229], in [regulon|protein:F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur regulon]
Biological materials
Mutant
MGNA-C066 (yclO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2064 NBRP B. subtilis, Japan]
BKE03810 (Δ[gene|EC63B5CDFDB4DF3A967ECEC40F2C44849311148B|fpbO]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AACGAGCAAAGCTATTTTCA, downstream forward: _UP4_TTGCTGTTAAAGGAGAATAA
BKK03810 (Δ[gene|EC63B5CDFDB4DF3A967ECEC40F2C44849311148B|fpbO]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AACGAGCAAAGCTATTTTCA, downstream forward: _UP4_TTGCTGTTAAAGGAGAATAA
References
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Time of last update: 2024-12-03 08:29:16
Author of last update: Jstuelk