yqjM
168
NADPH-dependent flavin oxidoreductase
locus
BSU_23820
Molecular weight
37.43 kDa
pI
5.14
function
reduction of double bonds of nonsaturated aldehydes
product
NADPH-dependent flavin oxidoreductase
essential
no
synonyms
yqjM
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1902 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,475,843 → 2,476,859
The protein
Catalyzed reaction/ biological activity
A + H+ + NADPH --> AH2 + NADP+ (according to UniProt)
Protein family
NADH:flavin oxidoreductase/NADH oxidase family (with [protein|9DC6FD87D1AF7CD2F41738E04C4D6DCD6F6276E5|yqiG], according to UniProt)
[wiki|Cofactors]
FMN [pubmed|15890652]
Structure
[PDB|1Z41] (oxidized form), [PDB|1Z48] (reduced form) [pubmed|15890652]
[AF|P54550]
Paralogous protein(s)
[protein|9DC6FD87D1AF7CD2F41738E04C4D6DCD6F6276E5|yqiG]
Expression and Regulation
Operons
genes
[gene|EB17629B7598C62741072E1AF0AB715C02041B70|yqjM]
description
[Pubmed|22383849]
regulation
induced in the presence of H2O2 [Pubmed|12660247]
Biological materials
Mutant
BKE23820 (Δ[gene|EB17629B7598C62741072E1AF0AB715C02041B70|yqjM]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTTTCGCCTCCCGTA, downstream forward: _UP4_TAATGCCCATAAGAGATATC
BKK23820 (Δ[gene|EB17629B7598C62741072E1AF0AB715C02041B70|yqjM]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTTTCGCCTCCCGTA, downstream forward: _UP4_TAATGCCCATAAGAGATATC
References
Reviews
Original Publications
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Time of last update: 2025-04-18 03:52:20
Author of last update: Melvin.boenninger