rpmH
168
ribosomal protein bL34
locus
BSU_41060
Molecular weight
5.00 kDa
pI
13
function
translation
product
ribosomal protein L34 (bL34)
essential
no
synonyms
rpmH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0230 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
4,215,255 → 4,215,389
Phenotypes of a mutant
severe slow-growth phenotype, suppressed by disruption of ''[gene|BE0777DE7C40825D4DB7252EA84AAB3892578529|mpfA]'' or overexpression of ''[gene|472E3A2407C83EEE26DB00079D185C4EA2988611|mgtE]'' [Pubmed|25182490]
increased fraction of hyperpolarized cells (35.2% vs. 3.7% in the wild type) [pubmed|30853217]
the [wiki|ribosome]s are destabilized [pubmed|25182490]
severely impaired for growth in the presence of 1.2 M NaCl [pubmed|35164567]
The protein
Catalyzed reaction/ biological activity
required for efficient 70S-[wiki|ribosome] formation [Pubmed|25182490]
Protein family
bacterial [wiki|ribosomal protein] bL34 family (single member, according to UniProt)
Structure
[PDB|3J9W] (the [wiki|ribosome]) [Pubmed|25903689]
[AF|P05647]
[wiki|Localization]
[wiki|ribosome]
Additional information
this ribosomal protein is lacking in some bacteria [pubmed|33753464]
Expression and Regulation
Operons
genes
[gene|EB07AECD3849CC0B65126DE27E71B28B3AD106B0|rpmH]
description
[Pubmed|2987847]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|2987848], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|EB07AECD3849CC0B65126DE27E71B28B3AD106B0|rpmH]-[gene|594F2D36BE71A45303A33AA2A2931F56F0A969ED|rnpA]-[gene|D40C202E67A5319A91811DB11356F47A56C97DD2|yidC1]-[gene|23D33E2D7AB1CA02165070DB8238957E3C768E64|jag]
description
[Pubmed|22383849]
regulation
expression is reduced in motile cells as compared to non-motile cells [pubmed|33782055]
Biological materials
Mutant
BKK41060 (Δ[gene|EB07AECD3849CC0B65126DE27E71B28B3AD106B0|rpmH]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK41060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTATGACACCTCCCTCG, downstream forward: _UP4_TAGGCCACTGAATAATGTCA
References
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Time of last update: 2024-12-25 21:53:19
Author of last update: Jstuelk