yhdF
168
similar to glucose 1-dehydrogenase
locus
BSU_09450
Molecular weight
31.36 kDa
pI
5.16
function
unknown
product
unknown
essential
no
synonyms
yhdF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1028 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,022,231 → 1,023,100
The protein
Protein family
[wiki|Short-chain dehydrogenases/reductases (SDR) family] (according to UniProt)
Structure
[PDB|3I30] (from Bacillus anthracis str. amesAncestor, 66% identity)
[AF|O07575]
Paralogous protein(s)
[protein|0DD474462720CAEE2AE17017BD7CA385238EBC6F|yxbG], [protein|0FD332269D2D6103E57ACE719E39977C68E38F0A|yvrD], [protein|20A7DBA142F3BF8DCAD9732BD908CE8CC79AA993|bacC], [protein|248F0805272FED9B38ECBB31E2872BC9EC163CE0|ymfI], [protein|3161519994609DA9360ED6E073E4A4C8C6210EFB|ydaD], [protein|439B468A13137000FB42E9389391CB4986FFED84|fabG], [protein|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|yoxD], [protein|CA4597C6253CCF7D7954686A30AF041808BDF8E5|gdh], [protein|CE990D33A12C50D22506A52E0099F7D97A762D4E|fadH]
[protein|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|kduD], (33.1%)
[protein|4DEFC2998464BF8327578C36A13A10DD277F991E|ykvO], (35,1%)
[protein|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC], (62.3%)
[protein|739B228743BC1FE9E6888E999BC0E4F615E36F9E|yhxD], (47%)
[protein|B6FF689E65906186F3576B378650D713DB84EDDA|ycdF], (34.3%)
[protein|D9D1FCBFC62F93CAA34DF61A784406F4E9EE6768|yjdA], (34%)
[protein|5964B6E817260DA7937796DDFA753A665A04D650|fabL], (30.1%)
[protein|0DD474462720CAEE2AE17017BD7CA385238EBC6F|yxbG] (36.1%), [protein|20A7DBA142F3BF8DCAD9732BD908CE8CC79AA993|bacC] (37.8%), [protein|439B468A13137000FB42E9389391CB4986FFED84|fabG] (31.6%), [protein|4DEFC2998464BF8327578C36A13A10DD277F991E|ykvO] (34.3%), [protein|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|kduD] (33.1%), [protein|CE990D33A12C50D22506A52E0099F7D97A762D4E|fadH] (31.1%), [protein|248F0805272FED9B38ECBB31E2872BC9EC163CE0|ymfI] (30,6%), [protein|D9D1FCBFC62F93CAA34DF61A784406F4E9EE6768|yjdA] (33.6%), [protein|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|yoxD] (31.9%), [protein|5964B6E817260DA7937796DDFA753A665A04D650|fabL] (30.1%), [protein|0FD332269D2D6103E57ACE719E39977C68E38F0A|yvrD] (30.2%)
Expression and Regulation
Operons
genes
[gene|EAEEA4DD9641919830A81185333A2610B964D37C|yhdF]
description
[Pubmed|22383849]
regulation
induced by stress ([protein|search|SigB]) [Pubmed|11544224]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
genes
[gene|6684F6083B001E9FDC5967799B715AE966B83E1D|citA]-[gene|EAEEA4DD9641919830A81185333A2610B964D37C|yhdF]
description
[Pubmed|22383849]
regulation
induced by stress ([protein|search|SigB]) [Pubmed|11544224]
regulatory mechanism
[protein|E7E0B170D1EEECE4E4EDC29B0399CB48253E9A17|citR]: repression, [Pubmed|8045899], in [regulon|protein:E7E0B170D1EEECE4E4EDC29B0399CB48253E9A17|citR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8045898], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
MGNA-B478 (yhdF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1477 NBRP B. subtilis, Japan]
BKE09450 (Δ[gene|EAEEA4DD9641919830A81185333A2610B964D37C|yhdF]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09450 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACATTCATCACTCCTAGAC, downstream forward: _UP4_TAATCAACGAAAAACCAGCT
BKK09450 (Δ[gene|EAEEA4DD9641919830A81185333A2610B964D37C|yhdF]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09450 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACATTCATCACTCCTAGAC, downstream forward: _UP4_TAATCAACGAAAAACCAGCT
References
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Time of last update: 2024-12-30 14:36:15
Author of last update: Jstuelk