ycbK
168
similar to efflux system
locus
BSU_02540
Molecular weight
33.81 kDa
pI
9.57
function
unknown
product
unknown
essential
no
ec
null
synonyms
ycbK
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0697 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
277,342 → 278,280
The protein
Protein family
[wiki|EamA transporter family] (according to UniProt)
[wiki|Domains]
[wiki|EamA domain] (aa 173-303) (according to UniProt)
Structure
[AF|P42243]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|354C71C2F6AFE620866D90595E6AC6CEFA5705C3|rtpA]-[gene|EAE919A6088F1A455B6FCE62BA8CCBD05C1F98D5|ycbK]
description
[Pubmed|10706627]
regulation
''[protein|search|rtpA]'': induced by tryptophan limitation ([protein|search|T-box] in the mRNA leader) [Pubmed|10706627]
regulatory mechanism
T-box: RNA switch, [protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|mtrB] [pubmed|10706627], in [regulon|other_regulator:T-box|T-box]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10706627], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Other regulations
[protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|mtrB]: translation inhibition
Biological materials
Mutant
MGNA-C033 (ycbK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2031 NBRP B. subtilis, Japan]
BKE02540 (Δ[gene|EAE919A6088F1A455B6FCE62BA8CCBD05C1F98D5|ycbK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02540 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCAGCTCAGCTTTTCT, downstream forward: _UP4_TAATTTTTATAAAACACACA
BKK02540 (Δ[gene|EAE919A6088F1A455B6FCE62BA8CCBD05C1F98D5|ycbK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02540 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCAGCTCAGCTTTTCT, downstream forward: _UP4_TAATTTTTATAAAACACACA
References
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Time of last update: 2025-04-28 19:08:39
Author of last update: Melvin.boenninger