ybdK
168
two-component sensor kinase
locus
BSU_02010
Molecular weight
37.12 kDa
pI
5.21
function
unknown
product
two-component sensor kinase
essential
no
ec
null
synonyms
ybdK
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0642 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
221,950 → 222,912
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of [protein|5F6D14A0B360832F9FD470668B006A628B109A56|ybdJ]
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
[wiki|Domains]
two transmembrane segments
[wiki|HAMP domain] (aa 67-120) (according to UniProt)
[wiki|Histidine kinase domain] (aa 135-320) (according to UniProt)
Structure
[AF|O31433]
Modification
autophosphorylation on a His residue
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|EA36C28A990EFFAEBFE279467A0B56B6B5F5255D|ybdK]
description
[http://dbtbs.hgc.jp/COG/prom/ybdK.html DBTBS]
regulatory mechanism
[protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK]: activation, in [regulon|protein:08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK regulon]
Biological materials
Mutant
MGNA-B957 (ybdK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1956 NBRP B. subtilis, Japan]
BKE02010 (Δ[gene|EA36C28A990EFFAEBFE279467A0B56B6B5F5255D|ybdK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACTGATATTTTGTCTTGA, downstream forward: _UP4_TGACCCCGCTGATGTTTTTC
BKK02010 (Δ[gene|EA36C28A990EFFAEBFE279467A0B56B6B5F5255D|ybdK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACTGATATTTTGTCTTGA, downstream forward: _UP4_TGACCCCGCTGATGTTTTTC
References
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Time of last update: 2024-12-20 16:26:37
Author of last update: Melvin.boenninger