bsrB
168
6S RNA, important for timing of [wiki|sporulation]
locus
BSU_misc_RNA_32
function
antagonist of [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]
product
6S RNA
essential
no
ec
null
synonyms
bsrB, 6S-2 RNA
Outlinks
Genomic Context
Categories containing this gene/protein
This gene is a member of the following regulons
Gene
Phenotypes of a mutant
increased [wiki|biofilm formation] (in undomesticated strains) [pubmed|32862759]
RNA
Catalyzed reaction/ biological activity
binds to [wiki|RNA polymerase] in [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]-dependent manner to repress transcription from a subgroup of promoters [pubmed|16336121]
Structure
[PDB|5VT0] (E. coli 6S RNA in complex with [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]-containing [wiki|RNA polymerase] holoenzyme) [pubmed|28988932]
additional information
paralog: [gene|A0E4AC7E74B5374198D047589629DA96A681CAF4|bsrA]
The protein
Structure
[PDB|5VT0] (E. coli 6S RNA in complex with [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]-containing [wiki|RNA polymerase] holoenzyme) [pubmed|28988932]
Expression and Regulation
Operons
genes
[gene|E85341621B3835F63F07C506E08B73A92E588B1F|bsrB]
description
[Pubmed|22383849]
genes
[gene|E85341621B3835F63F07C506E08B73A92E588B1F|bsrB]-[gene|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|recQ]-[gene|BEBA71A2EF56DAEAF80924856DA68124805BB158|yocH]
description
[Pubmed|22383849]
additional information
degradation is initiated by [protein|3EB289D0F58A58C693AB588798EE66A731341999|RNase J1] [pubmed|37369528]
References
Reviews
Research papers
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Time of last update: 2024-10-05 16:54:33
Author of last update: Jstuelk