cydB

cydB
168

cytochrome bd ubiquinol oxidase (subunit II), high affinity terminal oxidase

locus
BSU_38750
Molecular weight
37.70 kDa
pI
9.48
Protein length
Gene length
function
respiration
product
cytochrome bd ubiquinol oxidase (subunit II), high affinity terminal oxidase
essential
no
synonyms
cydB, yxkL

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1294 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,976,791 → 3,977,807
The protein
Catalyzed reaction/ biological activity
2 ubiquinol + n H+ + O2 --> 2  ubiquinone + n H+ + 2 H2O (according to UniProt)
Protein family
cytochrome ubiquinol oxidase subunit 2 family (with [protein|813E4BBEC8701114503ACD66DD6FE5A06B6B5E5F|ythB], according to UniProt)
[wiki|Cofactors]
heme b, heme d (according to UniProt)
Structure
[AF|P94365]
[wiki|Localization]
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|C0459C0D45E31561D281E016D86CD80DCAF13357|cydA]-[gene|E66EAB3C172ED8D1D26C675A7338B8153FB66987|cydB]-[gene|A65576E0261F1950A0DAD72B2432D97AB3EB2AA5|cydC]-[gene|244BF9E397FDB0691FFAA8C9D419B0AE417CACE1|cydD]
description
[Pubmed|16207915]
regulation
expressed under anaerobic conditions ([protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]) [Pubmed|17322317]
expression
expression is heterogeneous [pubmed|35171018]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|B5EF521437323EF43F08E5EFDB5C798616CA499A|rex]: repression, [Pubmed|15231791], in [regulon|protein:B5EF521437323EF43F08E5EFDB5C798616CA499A|rex regulon]
[protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]: activation, [Pubmed|17322317], in [regulon|protein:1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD regulon]
sigma factors
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [PubMed|16497325], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
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[gene|C0459C0D45E31561D281E016D86CD80DCAF13357|cydA]→[gene|244BF9E397FDB0691FFAA8C9D419B0AE417CACE1|cydD]

2024-10-05 12:19:58

Jstuelk

100

B656DC522BB35F8FB6BB0C0BBC86CB05C20AB7C7

80895031322ED50D8EABA337924455145A6261DF

Biological materials
Mutant
MGNA-B746 (cydB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1745 NBRP B. subtilis, Japan]
BKE38750 (Δ[gene|E66EAB3C172ED8D1D26C675A7338B8153FB66987|cydB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38750 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GATCATGAAGAGATGCCATG,  downstream forward: _UP4_CATAAGGAGCCTATGACTTA
BKK38750 (Δ[gene|E66EAB3C172ED8D1D26C675A7338B8153FB66987|cydB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38750 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GATCATGAAGAGATGCCATG,  downstream forward: _UP4_CATAAGGAGCCTATGACTTA
References
Reviews
33705278
Original Publications
16207915,17322317,15231791,9852001,10551842,15231791,17322317,35171018,36422766

E66EAB3C172ED8D1D26C675A7338B8153FB66987

Page visits: 2919

Time of last update: 2024-10-07 05:46:56

Author of last update: Jstuelk