yqfD
168
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]-dependent sporulation gene, similar to UDP-glucose 4-epimerase
locus
BSU_25350
Molecular weight
45.57 kDa
pI
10
function
sporulation
product
unknown
essential
no
synonyms
yqfD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5872 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,615,452 → 2,616,648
Phenotypes of a mutant
defect in sporulation [Pubmed|14523133]; some reduction in [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG] activity and production of small spores [Pubmed|26735940]
The protein
Structure
[AF|P54469]
[wiki|Localization]
polar (Septum) [Pubmed|16479537]
Expression and Regulation
Operons
genes
[gene|41CC88CC3AE4FDDA909CCEF2DED16B554341D81E|yqfC]-[gene|E5F5528DA775DE3EE2DD1EC931CDC7E3781E018C|yqfD]
description
[Pubmed|12662922]
regulation
expressed early during sporulation in the mother cell ([protein|search|SigE], [wiki|SpoIIID]) [Pubmed|12662922,15383836]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: repression, [Pubmed|15383836], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|12662922], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
MGNA-C444 (yqfD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2442 NBRP B. subtilis, Japan]
BKE25350 (Δ[gene|E5F5528DA775DE3EE2DD1EC931CDC7E3781E018C|yqfD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE25350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTCACAACATTTCCCCCTC, downstream forward: _UP4_CCTATTGTCAGGGAGACTGA
BKK25350 (Δ[gene|E5F5528DA775DE3EE2DD1EC931CDC7E3781E018C|yqfD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK25350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTCACAACATTTCCCCCTC, downstream forward: _UP4_CCTATTGTCAGGGAGACTGA
References
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Time of last update: 2024-12-21 08:59:03
Author of last update: Jstuelk