yerA
168
N6-methyladenosine deaminase
locus
BSU_06560
Molecular weight
66.47 kDa
pI
5.82
function
utilization of N6-methyladenosine
product
N6-methyladenosine deaminase
essential
no
ec
3.5.4.2
synonyms
yerA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1001 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
713,664 → 715,406
The protein
Catalyzed reaction/ biological activity
deamination of N6-methyladenosine [pubmed|34850126]
Protein family
[wiki|Metallo-dependent hydrolases superfamily] (according to UniProt)
[wiki|Cofactors]
Mn2+ [pubmed|34850126]
Structure
[AF|O34909]
Modification
phosphorylation on Ser-399 [Pubmed|17218307]
Expression and Regulation
Operons
genes
[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]-[gene|BE1F7BA77CE8B6A1A2D22F31421C27F2E954816A|yerB]-[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-A910 (yerA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/910 NBRP B. subtilis, Japan]
BKE06560 (Δ[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCACATACTCTCCTTTA, downstream forward: _UP4_TAAAATATAAAAGAGCAGGG
BKK06560 (Δ[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCACATACTCTCCTTTA, downstream forward: _UP4_TAAAATATAAAAGAGCAGGG
References
Page visits: 1991
Time of last update: 2024-12-20 19:57:36
Author of last update: Jstuelk