sodF
168
superoxide dismutase
locus
BSU_19330
Molecular weight
33.32 kDa
pI
6.17
function
detoxification of oxygen radicals
product
superoxide dismutase
essential
no
synonyms
sodF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0605 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,104,056 → 2,104,901
The protein
Catalyzed reaction/ biological activity
2 superoxide + 2 H+ --> O2 + H2O2 (according to UniProt)
Protein family
iron/manganese superoxide dismutase family (with [protein|6153A07B961017052E1072944B59F510D80CEC0F|sodA], according to UniProt)
[wiki|Cofactors]
contains an iron-sulfur cluster
Structure
[PDB|3EVK] (aa 80 ... 280, from Pyrobaculum aerophilum, 54% identity)
[AF|O35023]
Paralogous protein(s)
[protein|6153A07B961017052E1072944B59F510D80CEC0F|sodA]
Expression and Regulation
Operons
genes
[gene|24EB23F594F2B0EEA2E055857BA14FD9E361E0FD|sqhC]-[gene|E0645DD4A7A871457300139A7E5986EF11C07387|sodF]
description
[Pubmed|18436644]
regulation
expressed during sporulation in the mother cell [Pubmed|18436644]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190,18436644], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
BKE19330 (Δ[gene|E0645DD4A7A871457300139A7E5986EF11C07387|sodF]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE19330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTGAACATCTCCGCTTGAT, downstream forward: _UP4_TAAAAAAAGCCCCCTTTCCT
BKK19330 (Δ[gene|E0645DD4A7A871457300139A7E5986EF11C07387|sodF]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK19330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTGAACATCTCCGCTTGAT, downstream forward: _UP4_TAAAAAAAGCCCCCTTTCCT
References
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Time of last update: 2024-10-04 18:15:37
Author of last update: Melvin.boenninger