bstG
168
bacillithiol S-transferase, nuclease inhibitor
locus
BSU_05630
Molecular weight
19.76 kDa
pI
5.61
function
response to DNA damage
product
bacillithiol S-transferase, nuclease inhibitor
essential
no
synonyms
bstG, dinB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2318 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
608,246 → 608,764
Phenotypes of a mutant
reduced formation of [gene|F1969E4C7BAAF70BCBE570F58350C12A3E417539|rpsB] or [gene|144D952B05EBBFF41EC92DF906543EA00475FE69|rpsE] suppressor mutants after mitomycin treatment [pubmed|34339280]
The protein
Protein family
[wiki|S-transferase-like (STL) superfamily] [pubmed|29451913]
[wiki|DinB family] (according to UniProt)
Structure
[AF|Q02886]
Expression and Regulation
Operons
genes
[gene|DEB7605B4F6F5F365A49C1C15647F9767B01BF66|bstG]
description
[Pubmed|1847907]
regulation
induced by DNA damage ([protein|search|LexA]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8226626,8969214 PubMed]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA]: repression, [PubMed|8226626,8969214], in [regulon|protein:D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA regulon]
additional information
the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
Biological materials
Mutant
BKE05630 (Δ[gene|DEB7605B4F6F5F365A49C1C15647F9767B01BF66|bstG]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAAAATTCCCCCTTT, downstream forward: _UP4_TAAAAAAGCGGCTCCCTAAA
BKK05630 (Δ[gene|DEB7605B4F6F5F365A49C1C15647F9767B01BF66|bstG]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAAAATTCCCCCTTT, downstream forward: _UP4_TAAAAAAGCGGCTCCCTAAA
References
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Time of last update: 2025-04-15 03:26:03
Author of last update: Jstuelk