pssA
168
phosphatidylserine synthase
locus
BSU_02270
Molecular weight
19.47 kDa
pI
7.88
function
biosynthesis of phosphatidylethanolamine
product
phosphatidylserine synthase
essential
no
ec
2.7.8.8
synonyms
pssA, pss
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1183 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
247,744 → 248,277
The protein
Catalyzed reaction/ biological activity
CDP-1,2-diacyl-sn-glycerol + L-serine --> 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H+ (according to UniProt)
Protein family
CDP-alcohol phosphatidyltransferase class-I family (with [protein|2DB0071F2B747A7D5607C7A1B51564C25DC0BA8D|pgsA], according to UniProt)
Structure
[AF|P39823]
[wiki|Localization]
cell membrane at the septum [Pubmed|15743965]
Expression and Regulation
Operons
genes
[gene|27FB777AEBCC794A5A768C7FE7D8374BCEA75913|ybfK]-[gene|DE49797486CEC172F912D26A6BF2223190BF5DAD|pssA]-[gene|B2C089DCE51CA0CB11947FCD6F4EFAFF66269829|petA]-[gene|F34915697F3EF05E6A683055F46346C73F25CAFC|psd]
description
[Pubmed|22383849,14762009]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|14762009], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|E77364F274A520FCCA9F5C9504E317B047BA29E6|sigX]: sigma factor, [Pubmed|14762009], in [regulon|protein:E77364F274A520FCCA9F5C9504E317B047BA29E6|sigX regulon]
Biological materials
Mutant
BKE02270 (Δ[gene|DE49797486CEC172F912D26A6BF2223190BF5DAD|pssA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02270 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACAGTGTAACCAAACCTCC, downstream forward: _UP4_GCAGAAAACCTGGAGTCTGG
BKK02270 (Δ[gene|DE49797486CEC172F912D26A6BF2223190BF5DAD|pssA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02270 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACAGTGTAACCAAACCTCC, downstream forward: _UP4_GCAGAAAACCTGGAGTCTGG
References
Reviews
Original Publications
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Time of last update: 2024-12-19 14:04:23
Author of last update: Jstuelk