ydaE
168
lyxose isomerase, general stress protein, survival of ethanol stress and low temperatures
locus
BSU_04200
Molecular weight
19.11 kDa
pI
4.88
function
survival of ethanol stress and low temperatures
product
lyxose isomerase
essential
no
ec
null
synonyms
ydaE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3822 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
472,585 → 473,088
The protein
Catalyzed reaction/ biological activity
D-lyxose --> D-xylulose (according to UniProt)
Protein family
D-lyxose ketol-isomerase family (single member, according to UniProt)
Structure
[PDB|2Y0O] [Pubmed|21520290]
[AF|P96578]
Expression and Regulation
Operons
genes
[gene|3161519994609DA9360ED6E073E4A4C8C6210EFB|ydaD]-[gene|DDE975DA2E13759B0DB8B6D219760C2E2C6032FB|ydaE]
description
[Pubmed|22383849]
regulation
induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]) [Pubmed|15805528]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [pubmed|15805528,10220166], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
genes
[gene|3161519994609DA9360ED6E073E4A4C8C6210EFB|ydaD]-[gene|DDE975DA2E13759B0DB8B6D219760C2E2C6032FB|ydaE]-[gene|BFDAB855DC76A78C100DC5E5FB81F73069F5F93F|ydaF]-[gene|29342783A375260C5DAE920FBF6EC6EFD2D54DDE|ydaG]
description
[Pubmed|10220166]
regulation
induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]) [Pubmed|15805528]
expression
expression is increased upon depletion of depletion of tRNA maturation factors [gene|57A79AAF00243B5E058FA901D43AA7B55CA33F63|rnpB] or [gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz] [pubmed|36840557]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528,10220166], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
MGNA-C087 (ydaE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2085 NBRP B. subtilis, Japan]
BKE04200 (Δ[gene|DDE975DA2E13759B0DB8B6D219760C2E2C6032FB|ydaE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGCCCATATGTCTCACTC, downstream forward: _UP4_TAAGGATGGGCTTAACAGCC
BKK04200 (Δ[gene|DDE975DA2E13759B0DB8B6D219760C2E2C6032FB|ydaE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGCCCATATGTCTCACTC, downstream forward: _UP4_TAAGGATGGGCTTAACAGCC
References
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Time of last update: 2024-12-03 16:40:27
Author of last update: Melvin.boenninger