immR
168
transcriptional repressor ([wiki|Xre family]), controls expression of genes of the mobile genetic element ICEBs1, induction by the SOS response or the [protein|A208B4564A50D7BE2630DE40E8FAAF3C16236EE4|rapI]-[protein|F3E14B772A5DA9073ED806A9ADDD9B64F0DFDD5B|phrI] sensory system
locus
BSU_04820
Molecular weight
14.51 kDa
pI
4.99
function
control of transfer of the mobile genetic element ICEBs1
product
transcriptional repressor ([wiki|Xre family])
essential
no
synonyms
immR, ydcN
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1396 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
531,130 → 531,513
The protein
Protein family
[wiki|Xre family]
[wiki|Domains]
[wiki|HTH cro/C1-type domain] (aa 7-61) (according to UniProt)
Structure
[PDB|7T8I] [pubmed|35347179]
[AF|P96631]
Effectors of protein activity
binding of [protein|A208B4564A50D7BE2630DE40E8FAAF3C16236EE4|rapI] to ImmR results in loss of DNA-binding activity of ImmR and subsequently in induction of ImmR-repressed genes [Pubmed|17511812]
Expression and Regulation
Operons
genes
[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]-[gene|1599BBAC05EB62A847F73572CD777BC472301DE8|immA]-[gene|47AE982C5E71F31B5AF04C4F50593C2629F8EDAF|int]
description
[pubmed|22383849]
genes
[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]
description
[pubmed|22383849]
Biological materials
Mutant
BKE04820 (Δ[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTATCATCCATTTCA, downstream forward: _UP4_ATTGACGAATTAAAGAAGAA
BKK04820 (Δ[gene|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTATCATCCATTTCA, downstream forward: _UP4_ATTGACGAATTAAAGAAGAA
References
Reviews
Original Publications
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Time of last update: 2025-01-04 16:43:23
Author of last update: Jstuelk