cotS
168
outer spore coat protein
locus
BSU_30900
Molecular weight
40.93 kDa
pI
6.64
function
resistance of the spore
product
spore coat protein
essential
no
synonyms
cotS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5881 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,159,691 → 3,160,746
The protein
Protein family
cotS family (with [protein|D57116C65FD11EF92FB5D2945B10A1D024AEFF22|cotI] and [protein|0F40291BB10DB6D7DFD94B9C7D700F4410C4EE69|yutH], according to UniProt)
Structure
[PDB|2Q83] ([protein|D57116C65FD11EF92FB5D2945B10A1D024AEFF22|cotI], 26% identity) [pubmed|20077512]
[AF|P46914]
[wiki|Localization]
outer spore coat, localization depends on [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|cotE] [Pubmed|22171814]
Expression and Regulation
Operons
genes
[gene|2C17028E7DC755FFC190397AC6509E383C4DF99A|cotSA]-[gene|DC99E507696A1CB23140A1CBA45DA07D1F7C7D53|cotS]-[gene|5A13CEBB6820454E38DE81C1663078531B2AE4C2|ytxO]
description
[Pubmed|9603889]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|15699190,9603889]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|15383836], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,9603889], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
Biological materials
Mutant
BKE30900 (Δ[gene|DC99E507696A1CB23140A1CBA45DA07D1F7C7D53|cotS]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGGTACACTCTGTTCACCC, downstream forward: _UP4_AAAGCGTATCGGGAGGCGAA
BKK30900 (Δ[gene|DC99E507696A1CB23140A1CBA45DA07D1F7C7D53|cotS]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGGTACACTCTGTTCACCC, downstream forward: _UP4_AAAGCGTATCGGGAGGCGAA
References
Reviews
Original Publications
Page visits: 2008
Time of last update: 2024-12-22 02:34:50
Author of last update: Melvin.boenninger