cotM
168
spore coat protein (outer)
locus
BSU_17970
Molecular weight
15.08 kDa
pI
3.94
function
resistance of the spore
product
spore coat protein (outer)
essential
no
synonyms
cotM, yneL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0071 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,925,655 → 1,926,047
The protein
Structure
[AF|Q45058]
[wiki|Localization]
outer spore coat, localization depends on [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|cotE] [Pubmed|22171814]
Expression and Regulation
Operons
genes
[gene|DB8DC5B305DB5F301B047A2CA2089EC6485E7109|cotM]
description
[Pubmed|9068633]
regulation
expressed during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE]) [Pubmed|15383836,9068633]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: repression, [Pubmed|9068633], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|9068633], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
additional information
A [protein|search|ncRNA] is predicted between '[protein|search|yneK]' and '[protein|search|cotM]' [PubMed|20525796]
Biological materials
Mutant
BKE17970 (Δ[gene|DB8DC5B305DB5F301B047A2CA2089EC6485E7109|cotM]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCAACCTTGCTTTACA, downstream forward: _UP4_TAAACATAAAAAGTCACTTT
BKK17970 (Δ[gene|DB8DC5B305DB5F301B047A2CA2089EC6485E7109|cotM]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCAACCTTGCTTTACA, downstream forward: _UP4_TAAACATAAAAAGTCACTTT
References
Reviews
Original Publications
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Time of last update: 2024-12-30 18:42:48
Author of last update: Bzhu