ybbK
168
similar to [4Fe-4S]-dependent thiouracil desulfurase
locus
BSU_01720
Molecular weight
15.55 kDa
pI
5.31
function
detoxification of thiouracil
product
thiouracil desulfurase
essential
no
ec
null
synonyms
ybbK, tudS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1683 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
193,570 → 194,025
The protein
Catalyzed reaction/ biological activity
4-thiouracil --> uracil + H2S [pubmed|40139192]
Structure
[PDB|6Z92] (from an uncultured bacterium, 41% identity) [pubmed|32929873]
[AF|Q45584]
Biological materials
Mutant
BKE01720 (Δ[gene|DB52F9DB4212FABC87E41F374DCD2DEBCEEE4DF8|ybbK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE01720 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTGGTTTCTCCTCTCT, downstream forward: _UP4_GACATATTGTAAGGAGGCCA
BKK01720 (Δ[gene|DB52F9DB4212FABC87E41F374DCD2DEBCEEE4DF8|ybbK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK01720 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTGGTTTCTCCTCTCT, downstream forward: _UP4_GACATATTGTAAGGAGGCCA
References
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Time of last update: 2025-05-08 11:56:29
Author of last update: Jstuelk