katX
168
catalase, general stress protein
locus
BSU_38630
Molecular weight
62.19 kDa
pI
5.34
function
detoxification (degradation) of hydrogen peroxide
product
catalase (major catalase in spores)
essential
no
synonyms
katX, yxlI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0753 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,964,997 → 3,966,640
The protein
Catalyzed reaction/ biological activity
2 H2O2 --> 2 H2O + O2 (according to UniProt)
Protein family
[wiki|catalase family] (according to UniProt)
Structure
[PDB|4CAB] (from Deinococcus radiodurans, 69% identity) [pubmed|24975828]
[AF|P94377]
Paralogous protein(s)
[protein|B0A1AB6E920E6CBEE45115297599AF9A80972E38|katA], [protein|03FE63D6AAC77D6CEB052D0BF578ACD048C772FB|katE]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|DA5EB526EE8AF41BE9B837F2C276432BC4183AA1|katX]
description
[Pubmed|10503549]
regulation
expressed early during sporulation in the forespore ([protein|search|SigF], [protein|search|RsfA]) [Pubmed|16497325,15699190,10629188]
regulatory mechanism
[protein|7C0458DB0E3E3AC952FB9DDBC4AD220A3A456359|rsfA]: activation, [Pubmed|10629188], in [regulon|protein:7C0458DB0E3E3AC952FB9DDBC4AD220A3A456359|rsfA regulon]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|10503549,15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|10503549,16497325], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
Biological materials
Mutant
MGNA-B755 (katX::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1754 NBRP B. subtilis, Japan]
BKE38630 (Δ[gene|DA5EB526EE8AF41BE9B837F2C276432BC4183AA1|katX]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGGTTGGCCCTCCTTTT, downstream forward: _UP4_TAACAACAGCGAACAGGGCT
BKK38630 (Δ[gene|DA5EB526EE8AF41BE9B837F2C276432BC4183AA1|katX]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGGTTGGCCCTCCTTTT, downstream forward: _UP4_TAACAACAGCGAACAGGGCT
References
Page visits: 5110
Time of last update: 2024-12-22 06:23:44
Author of last update: Melvin.boenninger