tdk

tdk
168

thymidine kinase

locus
BSU_37060
Molecular weight
21.30 kDa
pI
5.69
Protein length
Gene length
function
biosynthesis of thymidine nucleotides
product
thymidine kinase (ATP:thymidine)
essential
no
ec
2.7.1.21
synonyms
tdk

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1435 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,802,405 → 3,802,992
The protein
Catalyzed reaction/ biological activity
ATP + thymidine --> ADP + dTMP + H+ (according to UniProt)
Protein family
thymidine kinase family (single member, according to UniProt)
Structure
[PDB|2JA1] (from B. cereus, 69% identity) [pubmed|17288553]
[AF|Q03221]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Biological materials
Mutant
BKE37060 (Δ[gene|D97D4CFDF7A9A48A8764738ECFD42F1D3A900BE7|tdk]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE37060 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAGGCTTCGCTCCCCTCT,  downstream forward: _UP4_TAGTCCAAAACATGGGTATA
BKK37060 (Δ[gene|D97D4CFDF7A9A48A8764738ECFD42F1D3A900BE7|tdk]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK37060 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATAGGCTTCGCTCCCCTCT,  downstream forward: _UP4_TAGTCCAAAACATGGGTATA
References
Research papers
17288553

D97D4CFDF7A9A48A8764738ECFD42F1D3A900BE7

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Time of last update: 2024-11-04 15:32:47

Author of last update: Melvin.boenninger