rpmGA
168
ribosomal protein bL33a
locus
BSU_24900
Molecular weight
5.85 kDa
pI
10.44
function
translation
product
ribosomal protein L33a (bL33a)
essential
no
synonyms
rpmGA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0267 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,574,408 → 2,574,557
The protein
Protein family
bacterial [wiki|ribosomal protein] bL33 family (with [protein|BBD82B93D5E880AB7093ED53DDB149B0E0B3BAE4|rpmGB] and [protein|5189DF2F6144CD2429B5C01B1AD03BAE98307579|rpmGC], according to UniProt)
[wiki|Cofactors]
requires zinc for activity [Pubmed|19648245]
Structure
[PDB|3J9W] (the [wiki|ribosome]) [Pubmed|25903689]
[AF|P56849]
Modification
phosphorylated on Arg-29 [Pubmed|22517742]
Paralogous protein(s)
[protein|BBD82B93D5E880AB7093ED53DDB149B0E0B3BAE4|rpmGB], [protein|5189DF2F6144CD2429B5C01B1AD03BAE98307579|rpmGC]
[wiki|Localization]
[wiki|ribosome] (according to UniProt)
Additional information
the protein is significantly underrepresented in 45S assembly intermediates that accumulate upon depletion of [protein|54CD247926F7FABE4ACE85EB7021B62500B47260|rbgA] [Pubmed|24335279,23700310]
Expression and Regulation
Operons
genes
[gene|D73FC9CAD929919050837824B4794F9FC9E83052|rpmGA]
description
[pubmed|22383849]
regulation
expression is reduced in motile cells as compared to non-motile cells [pubmed|33782055]
genes
[gene|402CD558623D1D520D3401F03CF021F42B3894A9|yqgL]-[gene|52BD8C536202E6D0B2B1F13E677CB2534F80BCEF|yqgM]-[gene|D73FC9CAD929919050837824B4794F9FC9E83052|rpmGA]
description
[Pubmed|22383849]
Biological materials
Mutant
BKE24900 (Δ[gene|D73FC9CAD929919050837824B4794F9FC9E83052|rpmGA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTATTTTCCCTCCAAACT, downstream forward: _UP4_TAACAGCTTTGCTGTTTGAG
BKK24900 (Δ[gene|D73FC9CAD929919050837824B4794F9FC9E83052|rpmGA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTATTTTCCCTCCAAACT, downstream forward: _UP4_TAACAGCTTTGCTGTTTGAG
References
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Time of last update: 2024-10-08 12:31:35
Author of last update: Jstuelk