ywjA
168
similar to [wiki|ABC transporter] (ATP-binding protein)
locus
BSU_37230
Molecular weight
64.39 kDa
pI
6.14
function
unknown
product
[wiki|ABC transporter] (ATP-binding protein)
essential
no
synonyms
ywjA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1132 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,819,754 → 3,821,481
The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]
[wiki|ABC transmembrane type-1 domain] (aa 16-299) (according to UniProt)
[wiki|ABC transporter domain] (aa 333-567) (according to UniProt)
Structure
[PDB|2HYD] (from Staphylococcus aureus, 38% identity) [pubmed|16943773]
[AF|P45861]
Paralogous protein(s)
[protein|E85814EDF232D21A42380D559EAD2CDFB41F19DB|yfiC], [protein|ED1F82463BAA28B67184BFAB5CB23CF26A62999D|bmrA], [protein|70D7098BEBD5E53B4B9B8C3394FAAF972C65EE22|yknU], [protein|C6B0ACB9D9703DD8141FD7D9D62DB22FB48F458B|yknV], [protein|0EB4D3E1B9AF39ECCBD79EB559FAE5BB0EE4C156|ygaD], [protein|67C0C9EA17EF953554D3D57CD0D285246F50C1AD|bmrC], [protein|288CA73D93B1E5106E1C6CE5E7E2E8BE2A6BD3F3|yfiB]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|07752EC6940F43DEBD1E9313A2A195E35EDB9F69|ywiE]-[gene|D5A3C316BD4567A0155F70330E32ACDE18F063FE|ywjA]-[gene|685B58AD2A02A0B48B7D4AAAE046DE2CF8F77C58|ywjB]
description
[pubmed|22383849]
regulatory mechanism
[protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]: repression, [pubmed|12354229], in [regulon|protein:F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur regulon]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|26577401], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
genes
[gene|D5A3C316BD4567A0155F70330E32ACDE18F063FE|ywjA]-[gene|685B58AD2A02A0B48B7D4AAAE046DE2CF8F77C58|ywjB]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-B662 (ywjA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1661 NBRP B. subtilis, Japan]
BKE37230 (Δ[gene|D5A3C316BD4567A0155F70330E32ACDE18F063FE|ywjA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE37230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCCTATCTTCCCCCAATG, downstream forward: _UP4_ATGGTGCATCGATAGGAGGA
BKK37230 (Δ[gene|D5A3C316BD4567A0155F70330E32ACDE18F063FE|ywjA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK37230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCCTATCTTCCCCCAATG, downstream forward: _UP4_ATGGTGCATCGATAGGAGGA
References
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Time of last update: 2024-10-10 12:20:45
Author of last update: Melvin.boenninger