yacC
168
similar to chaperonin (HSP33 Homolog), putative disulfide bond chaperone
locus
BSU_00710
Molecular weight
31.66 kDa
pI
4.66
function
unknown
product
putative disulfide bond chaperone
essential
no
synonyms
yacC, hslO
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1281 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
79,880 → 80,755
The protein
Protein family
HSP33 family (single member, according to UniProt)
Structure
[PDB|1VZY]
[AF|P37565]
[wiki|Localization]
cytoplasm (according to UniProt)
Expression and Regulation
Operons
genes
[gene|9B8EAD4EDDA97526D4462F6F3205F81FECD039DE|coaX]-[gene|D579A7E4D8C3DEE4F85586C5F721CAD5FE2BCA75|yacC]-[gene|548926987569033AA0C40610B8E80FB2BB8E1E3A|yacD]-[gene|D1FC976597E5583E40A4ED7234FBCA743AB01354|cysK]
description
[Pubmed|22383849]
regulation
induced by heat stress ([protein|2C6386E9A63F410558D168798D077DF91590F454|spx]) [pubmed|30480837]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [pubmed|30480837], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]: sigma factor, [pubmed|18179421], in [regulon|protein:081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM regulon]
genes
[gene|9B8EAD4EDDA97526D4462F6F3205F81FECD039DE|coaX]-[gene|D579A7E4D8C3DEE4F85586C5F721CAD5FE2BCA75|yacC]
description
[Pubmed|18179421]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]: sigma factor, [Pubmed|18179421], in [regulon|protein:081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM regulon]
Biological materials
Mutant
MGNA-B924 (yacC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1923 NBRP B. subtilis, Japan]
BKE00710 (Δ[gene|D579A7E4D8C3DEE4F85586C5F721CAD5FE2BCA75|yacC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE00710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAAATAATCCATTACTAAAC, downstream forward: _UP4_TAAGCTCTTTAGCGGGTTTT
BKK00710 (Δ[gene|D579A7E4D8C3DEE4F85586C5F721CAD5FE2BCA75|yacC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK00710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAAATAATCCATTACTAAAC, downstream forward: _UP4_TAAGCTCTTTAGCGGGTTTT
References
Research papers
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Time of last update: 2025-04-08 12:39:21
Author of last update: Jstuelk