ftsY
168
signal recognition particle
locus
BSU_15950
Molecular weight
36.19 kDa
pI
5.08
function
protein secretion
product
signal recognition particle
essential
yes
synonyms
ftsY, srb
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0552 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,670,140 → 1,671,129
Phenotypes of a mutant
essential [Pubmed|28189581]
The protein
Protein family
GTP-binding SRP family (with [protein|BB6F5D7463EF96E2C6344D0BC30A227C5E3B5817|flhF] and [protein|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh], according to UniProt)
Structure
[PDB|2XXA] (complex [protein|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]-[protein|D519765BF5261E48512CE86245BD7B733F188D4A|ftsY]-[protein|097C817A5A3E31F73F6ABC4AA95852A64E43A057|scr] RNA, from ''E. coli'') [Pubmed|21330537]
[AF|P51835]
[wiki|Localization]
cell membrane, peripheral, via N-terminal lipid-binding domain [Pubmed|19414018]
Expression and Regulation
Operons
genes
[gene|D519765BF5261E48512CE86245BD7B733F188D4A|ftsY]
description
[Pubmed|11021934]
regulation
expressed during vegetative growth and during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|11021934]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|11021934], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|11021934], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|11021934], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
genes
[gene|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|rnc]-[gene|0136394A52759CEEDD8DE074ED74033C6FFB8435|smc]-[gene|D519765BF5261E48512CE86245BD7B733F188D4A|ftsY]
description
[Pubmed|11021934]
regulation
expressed during vegetative growth and during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|11021934]
regulatory mechanism
stringent response: negative regulation, in [regulon|other_regulator:stringent response|stringent response]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|11021934], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
References
Reviews
Original Publications
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Time of last update: 2024-10-10 07:39:17
Author of last update: Jstuelk