cspC
168
cold shock protein
locus
BSU_05120
Molecular weight
7.12 kDa
pI
4.52
function
RNA chaperone
product
cold shock protein
essential
no
synonyms
cspC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1278 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
559,264 → 559,464
Phenotypes of a mutant
[gene|16E048FE5AF76CC771DEBBA8CB56B75A5414B3A2|cspB] [gene|D453E1E7D4256B56AFB2149731E08B104D59431B|cspC] double mutants are poorly viable at 15°C [pubmed|34361870]
The protein
[wiki|Domains]
[wiki|CSD domain] (aa 4-63) (according to UniProt)
Structure
[PDB|2I5M] ([protein|16E048FE5AF76CC771DEBBA8CB56B75A5414B3A2|cspB], 71% identity) [pubmed|17481655]
[AF|P39158]
Paralogous protein(s)
[protein|0F89D0B03F54B283CDD99A940D43C18E6B5703BB|cspD], [protein|16E048FE5AF76CC771DEBBA8CB56B75A5414B3A2|cspB]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|D453E1E7D4256B56AFB2149731E08B104D59431B|cspC]
description
[pubmed|22383849]
expression
expression is increased at low temperature [Pubmed|34361870]
Biological materials
Mutant
GP1969 (Δ[gene|D453E1E7D4256B56AFB2149731E08B104D59431B|cspC]::spec trpC2) available in [wiki|Jörg Stülke]'s lab [pubmed|34361870]
BKE05120 (Δ[gene|D453E1E7D4256B56AFB2149731E08B104D59431B|cspC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTGTTGCCTCCTAGT, downstream forward: _UP4_TAATCTTCAATCGTTTATAC
BKK05120 (Δ[gene|D453E1E7D4256B56AFB2149731E08B104D59431B|cspC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTTGTTGCCTCCTAGT, downstream forward: _UP4_TAATCTTCAATCGTTTATAC
two-hybrid system
B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in [wiki|Stülke] lab
lacZ fusion
GP1984 ([gene|DE4857E8A228F145EFB9B7AD817585258344ED1F|amyE]::(PcspC-lacZ cat) trpC2) available in [wiki|Jörg Stülke]'s lab [pubmed|34361870]
References
Page visits: 4626
Time of last update: 2025-04-04 04:47:32
Author of last update: Jstuelk