sndC
168
sulphur compound N-deacetylase
locus
BSU_10070
Molecular weight
43.11 kDa
pI
5.86
function
unknown
product
sulphur compound N-deacetylase
essential
no
synonyms
sndC, yhaA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1473 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,080,150 → 1,081,340
Phenotypes of a mutant
a ''[gene|0DE66A10D9475DC57A140561E8532D3EC038FD6F|sndA] [gene|C99AA3FDBB561BCED60915078DC746690C071753|sndB] [gene|D1A8D231369F0BF48639B61094B3222EC4605B79|sndC]'' triple mutant does not grow with N-acetyl cysteine and S-(2-succino)cysteine as the single sources of sulfur [Pubmed|23944997,29626092]
The protein
Protein family
[wiki|peptidase M20A family] (according to UniProt)
Structure
[PDB|4EWT] (from Staphylococcus aureus, 43% identity) [pubmed|23385746]
[AF|O07598]
Paralogous protein(s)
[protein|D6F1906CE8386F78F451D6B794F74DE4AD25AC9C|ykuR], [protein|0DE66A10D9475DC57A140561E8532D3EC038FD6F|sndA]
[protein|C99AA3FDBB561BCED60915078DC746690C071753|sndB], (38,8%)
Expression and Regulation
Operons
genes
[gene|D1A8D231369F0BF48639B61094B3222EC4605B79|sndC]
description
[Pubmed|12107147]
regulation
repressed by casamino acids [Pubmed|12107147]
genes
[gene|5EC5DD1844AD995AC1FA6FA76922C77CC514462D|yhfA]-[gene|D1A8D231369F0BF48639B61094B3222EC4605B79|sndC]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B500 (yhaA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1499 NBRP B. subtilis, Japan]
BKE10070 (Δ[gene|D1A8D231369F0BF48639B61094B3222EC4605B79|sndC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGCCGCTTCCCCCTTTT, downstream forward: _UP4_CTATAAAAAAACAGCCGGAG
BKK10070 (Δ[gene|D1A8D231369F0BF48639B61094B3222EC4605B79|sndC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGCCGCTTCCCCCTTTT, downstream forward: _UP4_CTATAAAAAAACAGCCGGAG
References
Page visits: 3822
Time of last update: 2024-11-10 02:12:58
Author of last update: Melvin.boenninger