prpE
168
protein tyrosine phosphatase
locus
BSU_11630
Molecular weight
27.31 kDa
pI
6.75
function
unknown
product
protein tyrosine phosphatase
essential
no
ec
3.6.1.17
synonyms
prpE, yjbP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
1,239,387 → 1,240,121
Phenotypes of a mutant
increased amounts of small aci-soluble spore proteins (SASPs) [Pubmed|21092197]
The protein
Catalyzed reaction/ biological activity
H2O + P1,P4-bis(5'-adenosyl) tetraphosphate --> AMP + ATP + 2 H+[pubmed|12059787]
H2O + P1,P4-bis(5'-guanosyl) tetraphosphate --> GMP + GTP + 2 H+ (according to UniProt)
Protein family
prpE family (single member, according to UniProt)
Structure
[PDB|4J6O] (PnkP from Thermocellum sp., 48% identity) [pubmed|23595150]
[AF|O31614]
[wiki|Localization]
forespore (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|D1661093571DA4DEC5FBD8EDD3910879DAFDEE23|prpE]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B162 (yjbP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1161 NBRP B. subtilis, Japan]
BKE11630 (Δ[gene|D1661093571DA4DEC5FBD8EDD3910879DAFDEE23|prpE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE11630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCGGTCTCCTCCTTACC, downstream forward: _UP4_CGCCCCATATAAAAAAGGAG
BKK11630 (Δ[gene|D1661093571DA4DEC5FBD8EDD3910879DAFDEE23|prpE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK11630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCGGTCTCCTCCTTACC, downstream forward: _UP4_CGCCCCATATAAAAAAGGAG
References
Reviews
Original Publications
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Time of last update: 2024-10-09 09:11:56
Author of last update: Jstuelk