nudF
168
involved in isopentenol (isoprenoid) biosynthesis, has RNA pyrophosphohydrolase activity
locus
BSU_23610
Molecular weight
20.84 kDa
pI
4.59
function
isoprenoid biosynthesis
product
unknown
essential
no
ec
3.6.1.13
synonyms
nudF, yqkG
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0494 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,458,509 → 2,459,066
The protein
Catalyzed reaction/ biological activity
ADP-D-ribose + H2O --> AMP + D-ribose 5-phosphate + 2 H+ (according to UniProt)
Protein family
[wiki|Nudix hydrolase] (according to UniProt)
[wiki|Domains]
[wiki|Nudix hydrolase domain] (aa 40-171) (according to UniProt)
Structure
[PDB|1V8I] (from ''Thermus thermophilus'', 38% identity) [Pubmed|15210687]
[AF|P54570]
Expression and Regulation
Operons
genes
[gene|CF38BE04F04919BB304789E9B3FE489385E468E6|nudF]-[gene|9D05B104000EED08FB62D6F362FC5E9C2A5354D9|yqxK]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-C410 (yqkG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2408 NBRP B. subtilis, Japan]
BKE23610 (Δ[gene|CF38BE04F04919BB304789E9B3FE489385E468E6|nudF]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23610 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTTCATCTCCCGTTC, downstream forward: _UP4_AAAGAAGCGCTCCAAGCACA
BKK23610 (Δ[gene|CF38BE04F04919BB304789E9B3FE489385E468E6|nudF]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23610 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTTCATCTCCCGTTC, downstream forward: _UP4_AAAGAAGCGCTCCAAGCACA
References
Page visits: 3924
Time of last update: 2024-10-13 01:09:33
Author of last update: Jstuelk