pgcM

pgcM
168

beta-phosphoglucomutase/ glucose-1-phosphate phosphodismutase

locus
BSU_34550
Molecular weight
24.95 kDa
pI
4.76
Protein length
Gene length
function
starch and maltodextrin utilization
product
beta-phosphoglucomutase(EC 5.4.2.6 and EC 2.7.1.41)
essential
no
ec
5.4.2.6
synonyms
pgcM, yvdM

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0637 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,546,873 → 3,547,553
The protein
Catalyzed reaction/ biological activity
β-D-glucose 1-phosphate --> β-D-glucose 6-phosphate (according to UniProt)
Protein family
[wiki|HAD superfamily] (according to UniProt)
CbbY/CbbZ/Gph/YieH family (with [protein|3DB9048B54C47E262997A2A5A0556AE607F93EA9|yhcW], according to UniProt)
Structure
[PDB|3NAS]
[AF|O06995]
Paralogous protein(s)
[protein|345EC248C0ADF48B0C25B175241AAE982E0E9B78|yhdA], (31%)
[protein|3DB9048B54C47E262997A2A5A0556AE607F93EA9|yhcW], (31%)
Expression and Regulation
Operons
genes
[gene|EA1BEC9FCFD2A32142A8A8E6D7362DB37E02052A|mdxR]-[gene|A577441DE4ABAF624D507DB80FBED2A652BCF385|yvdF]-[gene|5771E1976D986638B13ADDE97EDE32709E355923|mdxE]-[gene|EA2DD9892C1128ADCD6C8BC61248EBE45339E6D6|mdxF]-[gene|D72CFFE8ED3EC0280AE92C05A136D66ED1F62251|mdxG]-[gene|68C6FD5D4D9491EE15A5015447959A45C36EA702|yvdJ]-[gene|5F615BB886EC4F7000AAD42258DB8E47616552DE|yvdK]-[gene|6E5AB4620F9A896C32CD77AF314C67035814AE0A|malL]-[gene|CAFAE305B1771DD89E81F75A6713161393BE99A0|pgcM]
description
[Pubmed|16707683]
regulation
induced in the presence of starch, β-cyclomaltodextrin, or maltose [Pubmed|36723711,9573215]
regulatory mechanism
[protein|EA1BEC9FCFD2A32142A8A8E6D7362DB37E02052A|mdxR]: activation, [pubmed|36723711], in [regulon|protein:EA1BEC9FCFD2A32142A8A8E6D7362DB37E02052A|mdxR regulon]
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[gene|EA1BEC9FCFD2A32142A8A8E6D7362DB37E02052A|mdxR]→[gene|CAFAE305B1771DD89E81F75A6713161393BE99A0|pgcM]

2024-10-11 17:31:23

Jstuelk

110

875DD090FAB06D126BF7206081D457B6A5E12492

6EDA4FDB63800BE601694138B9C35457B6878679

Biological materials
Mutant
MGNA-B622 (yvdM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1621 NBRP B. subtilis, Japan]
BKE34550 (Δ[gene|CAFAE305B1771DD89E81F75A6713161393BE99A0|pgcM]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34550 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GTCTAAATCAAAAATGACCG,  downstream forward: _UP4_TGAAATGAAAAAAACCTGCA
BKK34550 (Δ[gene|CAFAE305B1771DD89E81F75A6713161393BE99A0|pgcM]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34550 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GTCTAAATCAAAAATGACCG,  downstream forward: _UP4_TGAAATGAAAAAAACCTGCA
References
11081794,16707683

CAFAE305B1771DD89E81F75A6713161393BE99A0

Page visits: 2475

Time of last update: 2024-10-11 23:25:42

Author of last update: Melvin.boenninger