ypnP
168
putative damage inducible, Na+ driven multidrug efflux pump
locus
BSU_21710
Molecular weight
48.31 kDa
pI
10.05
function
unknown
product
putative damage inducible, Na+ driven multidrug efflux pump
essential
no
synonyms
ypnP, dinF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0534 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,288,669 → 2,290,006
The protein
Protein family
[wiki|MOP exporter family]
[wiki|multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family] (according to UniProt)
Structure
[PDB|3VVO] (MATE multidrug exporter from Pyrococcus furiosus, 25% identity) [pubmed|23535598]
[AF|P54181]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|CA85B14720E86D2E609388D561B56ADA880B2190|ypnP]
description
(according to [http://dbtbs.hgc.jp/COG/prom/ypnP.html DBTBS]) null
Biological materials
Mutant
MGNA-A890 (ypnP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/890 NBRP B. subtilis, Japan]
BKE21710 (Δ[gene|CA85B14720E86D2E609388D561B56ADA880B2190|ypnP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE21710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTTTCTCCTTGTGTTC, downstream forward: _UP4_TAAGTGAAGCACTGCGAAAA
BKK21710 (Δ[gene|CA85B14720E86D2E609388D561B56ADA880B2190|ypnP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK21710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTTTCTCCTTGTGTTC, downstream forward: _UP4_TAAGTGAAGCACTGCGAAAA
References
Research papers
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Time of last update: 2024-10-06 11:41:13
Author of last update: Melvin.boenninger