azlC
168
amino acid exporter (with [protein|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD])
locus
BSU_26710
Molecular weight
28.22 kDa
pI
9.73
function
export of amino acids
product
component of amino acid exporter (with [protein|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD])
essential
no
synonyms
azlC, yrdH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1296 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,728,976 → 2,729,740
The protein
Catalyzed reaction/ biological activity
export of some branched-chain amino acids, histidine, and asparagine as well as 2,3-diaminopropionic acid (in complex with [protein|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]) [pubmed|38470260,36377869,38193659]
Protein family
azlC family (single member, according to UniProt)
Structure
[AF|O07942]
[wiki|Localization]
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB]-[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]-[gene|8BB8BDA602CC26B0A9E8C22666F0EC539306CF39|brnQ]-[gene|17FFEA4977F4F7334CFF7CD1C644DF14F599E6E6|yrdK]
description
[Pubmed|36377869,9287000]
regulation
repressed by [protein|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB] [Pubmed|36377869,9287000]
regulatory mechanism
[protein|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB]: repression, [Pubmed|36377869,9287000], in [regulon|protein:D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB regulon]
Biological materials
Mutant
GP3601 (Δ[gene|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB]-[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''kan'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
GP3622 (Δ[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''kan'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
GP3623 (Δ[gene|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB]-[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''spec'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
BKE26710 (Δ[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE26710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATCAACAACCTCCTACA, downstream forward: _UP4_GTATGACGATGACTATGACG
BKK26710 (Δ[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK26710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATCAACAACCTCCTACA, downstream forward: _UP4_GTATGACGATGACTATGACG
References
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Time of last update: 2024-12-20 13:05:12
Author of last update: Jstuelk