yqiD

yqiD
168

geranyltransferase

locus
BSU_24280
Molecular weight
29.59 kDa
pI
5.02
Protein length
Gene length
function
biosynthesis of peptidoglycan and teichoic acid
product
geranyltransferase
essential
no
ec
2.5.1.10
synonyms
yqiD, ispA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0142 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,525,789 → 2,526,679
Phenotypes of a mutant
The mutation of ''yqiD'' predisposes cells to grow without a wall [Pubmed|19212404]
The protein
Catalyzed reaction/ biological activity
(2E)-geranyl diphosphate + isopentenyl diphosphate --> (2E,6E)-farnesyl diphosphate + ppi (according to UniProt)
Protein family
FPP/GGPP synthase family (with [protein|3CAEA54E80A0B56EE120B881C8CDBE055AF6BDC1|hepT], according to UniProt)
[wiki|Cofactors]
Magnesium
Structure
[PDB|1RQI]: IspA from ''E. coli''.  Co-crystal with substrate isopentyl pyrophosphate and substrate analogue dimethyallyl S-thiolodiphosphate [Pubmed|14672944]
[AF|P54383]
Modification
None
Paralogous protein(s)
[protein|3CAEA54E80A0B56EE120B881C8CDBE055AF6BDC1|hepT]
Biological materials
Mutant
BKE24280 (Δ[gene|C75A4465688BCE9902F9CDC6DE069E36667377E1|yqiD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24280 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CCGGTCCGCCAGAAAGCTCG,  downstream forward: _UP4_TAAAACGATCCTAATTTGAA
BKK24280 (Δ[gene|C75A4465688BCE9902F9CDC6DE069E36667377E1|yqiD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24280 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CCGGTCCGCCAGAAAGCTCG,  downstream forward: _UP4_TAAAACGATCCTAATTTGAA
References
14672944,17114254,19212404,17458547,23452849,26051891

C75A4465688BCE9902F9CDC6DE069E36667377E1

Page visits: 4702

Time of last update: 2024-10-12 23:52:04

Author of last update: Jstuelk