fliD
168
filament cap, serves as an extracytoplasmic chaperone required for polymerization of [protein|E0BB77C8F1220E931D16A1FA6B75AE8907C76FDB|flagellin] into the helical filament
locus
BSU_35340
Molecular weight
54.33 kDa
pI
4.8
function
[category|SW.4.1.1|Motility and chemotaxis]
product
extracytoplasmic chaperone required for polymerization of [protein|E0BB77C8F1220E931D16A1FA6B75AE8907C76FDB|flagellin]
essential
no
synonyms
fliD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1345 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,632,911 → 3,634,407
Phenotypes of a mutant
the mutation suppresses the mucoid phenotype of ''[gene|86C729C7D5ABEE519ADC4A893940600BBB655EF1|motA]'' or ''[gene|FE56753D061344B0F10A6523F49C5C7356AA40B6|motB]'' mutants [Pubmed|24296669]
defective in [category|SW.4.1.4|Swarming] motility [pubmed|35638827]
The protein
Protein family
fliD family (single member, according to UniProt)
Structure
[PDB|5FHY] (from Pseudomonas aeruginosa, 26% identity) [pubmed|27664419]
[AF|P39738]
[wiki|Localization]
extracellular (no signal peptide) [Pubmed|18957862]
Expression and Regulation
Operons
genes
[gene|4DBF4635B5C5A7541E8F97440D139DAA02547B99|yvyC]-[gene|C6012DEA301DF5B2DDD7E673A736BD3E5163F209|fliD]-[gene|4882FAD988FEDD0E72E4CAFB10C8DE61DDAC23B0|fliS]-[gene|4DE156D248FAF7DE3ED9AC35F006B5319A3C1BDA|fliT]-[gene|A6E7212D159F076F5D26F9C02F340B40C3667623|smiA]-[gene|06FEA5F205B40DD5CF8D9F1328E940D4543F4741|S1350]-[gene|37B8B671B84266A7D65B90A9077A0DFF458D1851|hpf]
description
[pubmed|22383849]
sigma factors
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|26577401], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
genes
[gene|4DBF4635B5C5A7541E8F97440D139DAA02547B99|yvyC]-[gene|C6012DEA301DF5B2DDD7E673A736BD3E5163F209|fliD]-[gene|4882FAD988FEDD0E72E4CAFB10C8DE61DDAC23B0|fliS]-[gene|4DE156D248FAF7DE3ED9AC35F006B5319A3C1BDA|fliT]
description
[Pubmed|8195064]
sigma factors
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|8195064], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
Biological materials
Mutant
BKE35340 (Δ[gene|C6012DEA301DF5B2DDD7E673A736BD3E5163F209|fliD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE35340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GACCATCTCAAACCACTCCT, downstream forward: _UP4_TAAATGTAATTTGGAGGATG
BKK35340 (Δ[gene|C6012DEA301DF5B2DDD7E673A736BD3E5163F209|fliD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK35340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GACCATCTCAAACCACTCCT, downstream forward: _UP4_TAAATGTAATTTGGAGGATG
References
Reviews
Original Publications
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Time of last update: 2024-12-21 02:00:49
Author of last update: Jstuelk