yuiE
168
similar to leucyl aminopeptidase
locus
BSU_32050
Molecular weight
53.49 kDa
pI
4.55
function
unknown
product
unknown
essential
no
synonyms
yuiE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0260 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,296,417 → 3,297,919
The protein
Catalyzed reaction/ biological activity
Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low (according to UniProt)
Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids (according to UniProt)
Protein family
peptidase M17 family (single member, according to UniProt)
Structure
[PDB|3H8E] (from Pseudomonas putida 37% identity) [pubmed|20359484]
[AF|O32106]
Expression and Regulation
Operons
genes
[gene|C5A6D0D68DFF0459FBBF146854A9F6098E9A3BE8|yuiE]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B569 (yuiE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1568 NBRP B. subtilis, Japan]
BKE32050 (Δ[gene|C5A6D0D68DFF0459FBBF146854A9F6098E9A3BE8|yuiE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAGGCTTACACTCCTAA, downstream forward: _UP4_TAATGAAAAATCCCTGCTGT
BKK32050 (Δ[gene|C5A6D0D68DFF0459FBBF146854A9F6098E9A3BE8|yuiE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAGGCTTACACTCCTAA, downstream forward: _UP4_TAATGAAAAATCCCTGCTGT
References
Research papers
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Time of last update: 2025-04-12 14:45:59
Author of last update: Jstuelk