ykfA

ykfA
168

similar to LD-carboxypeptidase; may cleave C-terminal D-Ala from peptidoglycan tetrapeptides

Locus
BSU_12970
Molecular weight
25.26 kDa
Isoelectric point
5.41
Protein length
319 aaSequenceBlast
Gene length
960 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
ykfA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1619 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,365,888 → 1,366,847
The protein
Protein family
peptidase S66 family (with YocD, according to UniProt)
Structure
3SR3 (PDB) (MccF from B. anthracis, 30% identity) PubMed
5Z01 (PDB) (LdcA from E. coli, 30% identity) PubMed
O34851 (AlphaFold)
Expression and Regulation
Operons
Genes
dppA-dppB-dppC-dppD-dppE-ykfA-ykfB-ykfC-ykfD
Description
PubMed
Regulatory mechanism
CodY: repression, PubMed, in codY regulon
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dppA->ykfD

2025-03-27 02:00:36

Bzhu

140

9978370314fc05087eca13c4f3ce94e92ce93ff2

E2A0CC9BE866DBD9F0E3A5F48EE05465C14EFD9D

Biological materials
Mutant
MGNA-A740 (ykfA::erm), available at the NBRP B. subtilis, Japan
BKE12970 (ΔykfA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGCTCTGCACCCTACG,  downstream forward: _UP4_GTTTCAGAAGGGGCGCTGAA
BKK12970 (ΔykfA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGCTCTGCACCCTACG,  downstream forward: _UP4_GTTTCAGAAGGGGCGCTGAA
References
Reviews
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Original Publications
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C4F85F85F0C99A59145961E34B19D3AD03D2BC22

Page visits: 2371

Time of last update: 2025-04-08 14:37:00

Author of last update: Jstuelk