aseA
168
As(III) efflux pump
locus
BSU_05340
Molecular weight
47.16 kDa
pI
8.97
function
resistance to arsenite
product
As(III) efflux pump
essential
no
ec
null
synonyms
aseA, ydfA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1055 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
579,889 → 581,196
The protein
Protein family
ArsB family (with [protein|EB8E3F88BC1ED2BAD5A98D609EDAA002261150A5|ywrK], according to UniProt)
Structure
[AF|P96678]
Paralogous protein(s)
[protein|EB8E3F88BC1ED2BAD5A98D609EDAA002261150A5|ywrK]
Expression and Regulation
Operons
genes
[gene|D169C58739F17EE0D341D015592FF07CBBE1B6E1|aseR]-[gene|C0E921ECAEE12DEC32A5DEE866762D6971360FA1|aseA]-[gene|6BA4A8575050B1BA45FF98E1F3B1F27F6C24A5E4|ydzS/1]-[gene|009BB4460A9374A8259DE7BD05724467198E0A90|ydzS/2]
description
[pubmed|22383849]
regulation
induced by As(III) ([protein|D169C58739F17EE0D341D015592FF07CBBE1B6E1|aseR]) [Pubmed|15948947]
regulatory mechanism
[protein|D169C58739F17EE0D341D015592FF07CBBE1B6E1|aseR]: repression, [Pubmed|15948947], in [regulon|protein:D169C58739F17EE0D341D015592FF07CBBE1B6E1|aseR regulon]
Biological materials
Mutant
MGNA-C141 (ydfA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2139 NBRP B. subtilis, Japan]
BKE05340 (Δ[gene|C0E921ECAEE12DEC32A5DEE866762D6971360FA1|aseA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGATGTCAATCTAATGC, downstream forward: _UP4_TAAAAGGACAAGGTCACTAT
BKK05340 (Δ[gene|C0E921ECAEE12DEC32A5DEE866762D6971360FA1|aseA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGATGTCAATCTAATGC, downstream forward: _UP4_TAAAAGGACAAGGTCACTAT
References
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Time of last update: 2025-04-06 07:56:39
Author of last update: Melvin.boenninger