ykuT
168
mechanosensitive channel, similar to MscS, general stress protein
locus
BSU_14210
Molecular weight
29.88 kDa
pI
5.65
function
resistance to osmotic downshock
product
anion-selective mechanosensitive channel of small conductance
essential
no
synonyms
ykuT
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0668 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,491,221 → 1,492,024
The protein
Protein family
[wiki|MscS (TC 1.A.23) family] (according to UniProt)
Structure
[PDB|3T9N] (from Thermoanaerobacter tengcongensis, 40% identity) [pubmed|23074248]
[AF|O34897]
[wiki|Localization]
cell membrane [Pubmed|19252899]
Expression and Regulation
Operons
genes
[gene|C0C65835A0E2680F52D391BF4EAB7F463FBB1DD3|ykuT]
description
[pubmed|22383849]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
MGNA-B342 (ykuT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1341 NBRP B. subtilis, Japan]
1A960 ( ''ykuT''::''cat''), [Pubmed|18310427], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A960&Search=1A960 BGSC]
BKE14210 (Δ[gene|C0C65835A0E2680F52D391BF4EAB7F463FBB1DD3|ykuT]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTGAGCTCCTTTTCTA, downstream forward: _UP4_TAAATAAAAGAACCGAAGCT
BKK14210 (Δ[gene|C0C65835A0E2680F52D391BF4EAB7F463FBB1DD3|ykuT]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTGAGCTCCTTTTCTA, downstream forward: _UP4_TAAATAAAAGAACCGAAGCT
References
Reviews
Original Publications
Labs working on this gene/protein
[wiki|Erhard Bremer], University of Marburg, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi homepage]
Page visits: 3265
Time of last update: 2024-12-21 16:21:02
Author of last update: Jstuelk