chrS
168
transcriptional repressor ([wiki|Lrp family]) of the [gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]-[gene|E63704C51B53F05BAD9B35D3B6874DB9231B6D24|ywrB]-[gene|70CC5C9BCC676AB89C0BF80686BD98BA08FAE648|ywrA] operon
locus
BSU_36110
Molecular weight
17.98 kDa
pI
5.84
function
regulation of chromate export
product
transcriptional repressor ([wiki|Lrp family])
essential
no
synonyms
chrS, ywrC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1522 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,720,925 → 3,721,401
The protein
Protein family
[wiki|Lrp family]
[wiki|Domains]
[wiki|HTH asnC-type domain] (aa 12-73) (according to UniProt)
Structure
[PDB|1RI7] (from Pyrococcus sp., 31% identity) [pubmed|14976242]
[AF|O05217]
Expression and Regulation
Operons
genes
[gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]-[gene|E63704C51B53F05BAD9B35D3B6874DB9231B6D24|ywrB]-[gene|70CC5C9BCC676AB89C0BF80686BD98BA08FAE648|ywrA]
description
[Pubmed|22383849]
regulatory mechanism
[protein|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]: repression, [Pubmed|23989926], in [regulon|protein:C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|23989926], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-A533 (ywrC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/533 NBRP B. subtilis, Japan]
BKE36110 (Δ[gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE36110 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTGCTCCACCTGCTTTC, downstream forward: _UP4_ATGAAGCTGTAAAGGAGAGA
BKK36110 (Δ[gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK36110 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTGCTCCACCTGCTTTC, downstream forward: _UP4_ATGAAGCTGTAAAGGAGAGA
References
Research papers
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Time of last update: 2024-12-24 20:16:58
Author of last update: Melvin.boenninger