rpsR
168
ribosomal protein bS18
locus
BSU_40890
Molecular weight
8.83 kDa
pI
11.49
function
translation
product
ribosomal protein S18 (bS18)
essential
yes
synonyms
rpsR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0238 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
4,198,603 → 4,198,842
Phenotypes of a mutant
essential [Pubmed|23002217,12682299]
The protein
Protein family
bacterial [wiki|ribosomal protein] bS18 family (single member, according to UniProt)
Structure
[PDB|3J9W] (the [wiki|ribosome]) [Pubmed|25903689]
[AF|P21475]
Modification
acetylated by [protein|C2283BDD806221A285A27F24F52F92F4D47F0C55|rimI] [pubmed|18596200]
Expression and Regulation
Operons
genes
[gene|BD162A17E5F3F9AB49E478CE72D0FE92D82E6673|yyzM]-[gene|FEE1952DFA3D6A5E2DC108B3B203B526642E2C68|yyaE]-[gene|C0F5FAD6DF89DA9E0FFC8F888D7CED6AA42D9C73|yyaF]-[gene|9D25B8F4579C41E77AE9CDD18CAD6DA37F3DD0A2|rpsF]-[gene|8DE39680CA7663803A107066FBE9AFFCC77DB72A|ssbA]-[gene|C0B926F1134A7A3FEEC886F9AF67F694C8E0C089|rpsR]
description
[Pubmed|22383849]
genes
[gene|C0F5FAD6DF89DA9E0FFC8F888D7CED6AA42D9C73|yyaF]-[gene|9D25B8F4579C41E77AE9CDD18CAD6DA37F3DD0A2|rpsF]-[gene|8DE39680CA7663803A107066FBE9AFFCC77DB72A|ssbA]-[gene|C0B926F1134A7A3FEEC886F9AF67F694C8E0C089|rpsR]
description
[Pubmed|14762004]
regulation
[protein|search|ComK]: transcription activation [Pubmed|11948146]
regulatory mechanism
[protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK]: activation, in [regulon|protein:08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK regulon]
stringent response: negative regulation, in [regulon|other_regulator:stringent response|stringent response]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|24310371], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|9D25B8F4579C41E77AE9CDD18CAD6DA37F3DD0A2|rpsF]-[gene|8DE39680CA7663803A107066FBE9AFFCC77DB72A|ssbA]-[gene|C0B926F1134A7A3FEEC886F9AF67F694C8E0C089|rpsR]
description
[Pubmed|24310371,22383849]
regulation
[protein|search|ComK]: transcription activation [Pubmed|11948146]
additional information
the mRNA is very stable (> 15 min) [pubmed|12884008]
Biological materials
two-hybrid system
B. pertussis adenylate cyclase-based bacterial two hybrid system ([wiki|BACTH]), available in [wiki|Jörg Stülke]'s lab
References
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Time of last update: 2025-01-14 11:38:36
Author of last update: Jstuelk