yvaK
168
general stress protein, carboxylesterase
locus
BSU_33620
Molecular weight
28.26 kDa
pI
4.99
function
unknown
product
unknown
essential
no
ec
3.1.1.1
synonyms
yvaK, est, fphH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1647 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,454,221 → 3,454,967
The protein
Catalyzed reaction/ biological activity
carboxylic ester + H2O --> carboxylate + alcohol + H+ (according to UniProt)
Protein family
lipase/esterase LIP3/BchO family (single member, according to UniProt)
Structure
[PDB|1TQH] (Geobacillus stearothermophilus)
[PDB|8FTP] (Staphylococcus aureus) [pubmed|37824340]
[AF|O32232]
Expression and Regulation
Operons
genes
[gene|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG]-[gene|C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8|yvaK]-[gene|0472A4346ADA1DC41C9D00E8F3222A0EBB76DFA8|rnr]-[gene|D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A|smpB]-[gene|5C12BB19B975F7FEBCFA119DAC66338C20FCECFA|ssrA]
description
[Pubmed|17369301]
regulation
''[protein|search|yvaK]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
genes
[gene|C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8|yvaK]-[gene|0472A4346ADA1DC41C9D00E8F3222A0EBB76DFA8|rnr]-[gene|D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A|smpB]-[gene|5C12BB19B975F7FEBCFA119DAC66338C20FCECFA|ssrA]
description
[Pubmed|17369301]
regulation
''[protein|search|yvaK]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]
Biological materials
Mutant
MGNA-B606 (yvaK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1605 NBRP B. subtilis, Japan]
BKE33620 (Δ[gene|C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8|yvaK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33620 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCTCATGTCTCCCTTTC, downstream forward: _UP4_TGGTAATCAACAGGAGGTCG
BKK33620 (Δ[gene|C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8|yvaK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33620 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCTCATGTCTCCCTTTC, downstream forward: _UP4_TGGTAATCAACAGGAGGTCG
References
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Time of last update: 2024-10-09 10:04:11
Author of last update: Jstuelk