yqgT
168
similar to gamma-D-glutamyl-L-diamino acid endopeptidase I
locus
BSU_24830
Molecular weight
43.28 kDa
pI
5.91
function
cell wall metabolism
product
peptidoglycan hydrolase
essential
no
synonyms
yqgT
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2866 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,567,360 → 2,568,490
The protein
Catalyzed reaction/ biological activity
cleaves the peptide bond between D-Glu (position 2 in the peptioglycan peptide) and m-diamino pimelic acid (position 3) [Pubmed|18266855]
has both endopeptidase and carboxypeptidase activities [Pubmed|18266855]
Protein family
peptidase M14 family (single member, according to UniProt)
[wiki|Cofactors]
Zn
Structure
[AF|P54497]
[wiki|Localization]
extracellular space (according to UniProt)
Expression and Regulation
Operons
genes
[gene|C0192CFF5259B6C9AEB995E5064C2AADF33ED4D3|yqgT]-[gene|1A070D28C3DB109F67A5E73C5F0734177995E286|yqgU]-[gene|1CC5837E19A99368962E84FC034C63F4382EE735|yqgV]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-C480 (yqgT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2478 NBRP B. subtilis, Japan]
BKE24830 (Δ[gene|C0192CFF5259B6C9AEB995E5064C2AADF33ED4D3|yqgT]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCATCCCCCTTTTTTGTT, downstream forward: _UP4_TAACTGAAACTTTTTCTTTT
BKK24830 (Δ[gene|C0192CFF5259B6C9AEB995E5064C2AADF33ED4D3|yqgT]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCATCCCCCTTTTTTGTT, downstream forward: _UP4_TAACTGAAACTTTTTCTTTT
References
Reviews
Original Publications
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Time of last update: 2024-12-20 10:00:34
Author of last update: Melvin.boenninger