ytrB
168
[wiki|ABC transporter] (ATP-binding protein)
locus
BSU_30450
Molecular weight
33.67 kDa
pI
5.51
function
unknown
product
[wiki|ABC transporter] (ATP-binding protein)
essential
no
synonyms
ytrB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1131 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,117,976 → 3,118,854
The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transporter domain] (aa 2-227) (according to UniProt)
Structure
[PDB|1VPL] (from Thermotoga maritima, 31% identity)
[AF|O34641]
[wiki|Localization]
cell membrane (via [protein|31977FDC549E45911C333623DCA3D8941A93D8FF|ytrC]-[protein|9C8233C48733A1E9271EE7AA1283EA9F446CF9DA|ytrD]) [Pubmed|10986249]
Expression and Regulation
Operons
genes
[gene|DCFA6025F7B4D7C5F6FB8107DDA6538CED33084D|ytrG]-[gene|6A074CE9AD98A2751A216A2EA8156ACE6FFC7280|ytrA]-[gene|BF81AD95FE6CF7662D012EF293C769E80C093D34|ytrB]-[gene|31977FDC549E45911C333623DCA3D8941A93D8FF|ytrC]-[gene|9C8233C48733A1E9271EE7AA1283EA9F446CF9DA|ytrD]-[gene|4FE6A51A0D9BBBF574EA2EF18B95B5BFC0A64CCB|ytrE]-[gene|9024AB63030C1934A954EE6A378CADBDC977E863|ytrF]
description
[Pubmed|10986249,21856850]
regulation
expressed early in the stationary phase [Pubmed|10986249]
regulatory mechanism
[protein|6A074CE9AD98A2751A216A2EA8156ACE6FFC7280|ytrA]: repression, [Pubmed|10986249,21856850], in [regulon|protein:6A074CE9AD98A2751A216A2EA8156ACE6FFC7280|ytrA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10986249,21856850], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
GP3188 (Δ[gene|BF81AD95FE6CF7662D012EF293C769E80C093D34|ytrB]), available in [wiki|Jörg Stülke]'s lab [pubmed|33897624]
GP2646 Δ([gene|DCFA6025F7B4D7C5F6FB8107DDA6538CED33084D|ytrG]-[gene|6A074CE9AD98A2751A216A2EA8156ACE6FFC7280|ytrA]-[gene|BF81AD95FE6CF7662D012EF293C769E80C093D34|ytrB]-[gene|31977FDC549E45911C333623DCA3D8941A93D8FF|ytrC]-[gene|9C8233C48733A1E9271EE7AA1283EA9F446CF9DA|ytrD]-[gene|4FE6A51A0D9BBBF574EA2EF18B95B5BFC0A64CCB|ytrE]-[gene|9024AB63030C1934A954EE6A378CADBDC977E863|ytrF])::''ermC'', available in [wiki|Jörg Stülke]'s lab [pubmed|33897624]
MGNA-A131 (ytrB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/131 NBRP B. subtilis, Japan]
BKE30450 (Δ[gene|BF81AD95FE6CF7662D012EF293C769E80C093D34|ytrB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30450 BGSC] and in [wiki|Jörg Stülke]'s lab, [Pubmed|28189581], upstream reverse: _UP1_GTTCAATCATTTTTTTTGCC, downstream forward: _UP4_AGATGGTAGACCGAGGTCTC
BKK30450 (Δ[gene|BF81AD95FE6CF7662D012EF293C769E80C093D34|ytrB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30450 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTCAATCATTTTTTTTGCC, downstream forward: _UP4_AGATGGTAGACCGAGGTCTC
References
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Time of last update: 2024-10-11 22:41:08
Author of last update: Jstuelk