pit
168
low-affinity inorganic phosphate transporter, proton symporter
locus
BSU_12840
Molecular weight
34.63 kDa
pI
10.45
function
phosphate uptake
product
low-affinity inorganic phosphate transporter, proton symporter
essential
no
synonyms
pit, ykaB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0306 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,349,468 → 1,350,469
The protein
Protein family
inorganic phosphate transporter (PiT) (TC 2.A.20) family (with [protein|58A5A7F12664EC38AC21E24C1AD89671D7E648CF|cysP], according to UniProt)
Structure
[AF|O34436]
[wiki|Localization]
membrane associated [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|BBA93C5BAA044DA61A2D1E0EE850A12391E8A3E3|ykaA]-[gene|BBFA6A5EE16CE6203AF89573F87678395277C9E8|pit]
description
[Pubmed|22383849]
regulation
repressed under conditions that trigger sporulation ([wiki|Spo0A]) [Pubmed|14651647]
regulatory mechanism
[protein|2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A]: repression, [Pubmed|14651647], in [regulon|protein:2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A regulon]
Biological materials
Mutant
MGNA-A735 (pit::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/735 NBRP B. subtilis, Japan]
BKE12840 (Δ[gene|BBFA6A5EE16CE6203AF89573F87678395277C9E8|pit]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE12840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAGAATATCCATTTTTACCC, downstream forward: _UP4_TAATGTCACACCGCTTCTGT
BKK12840 (Δ[gene|BBFA6A5EE16CE6203AF89573F87678395277C9E8|pit]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK12840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAGAATATCCATTTTTACCC, downstream forward: _UP4_TAATGTCACACCGCTTCTGT
References
Reviews
Original Publications
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Time of last update: 2024-12-30 10:53:04
Author of last update: Melvin.boenninger