yrpC
168
glutamate racemase
locus
BSU_26810
Molecular weight
29.73 kDa
pI
6.74
function
peptidoglycan precursor biosynthesis
product
glutamate racemase
essential
no
ec
5.1.1.3
synonyms
yrpC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0796 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,738,308 → 2,739,105
The protein
Catalyzed reaction/ biological activity
L-glutamate --> D-glutamate (according to UniProt)
Protein family
aspartate/glutamate racemases family (with [protein|36FF9F097682D8BA8D7359BFEAF71ACE8E9E90D8|racE] and [protein|2ABCC493C6CA847A7BC65B1200A9B6490621462A|racX], according to UniProt)
Structure
[PDB|2JFN] (from ''Escherichia coli'', 36% identity, 54% similarity) [Pubmed|17568739]
[AF|O05412]
Paralogous protein(s)
[protein|36FF9F097682D8BA8D7359BFEAF71ACE8E9E90D8|racE]
Expression and Regulation
Operons
genes
[gene|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|yrpC]
description
[Pubmed|22383849]
regulation
expressed only in minimal medium, not in complex medium [Pubmed|15347750]
Biological materials
Mutant
MGNA-A867 (yrpC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/867 NBRP B. subtilis, Japan]
BKE26810 (Δ[gene|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|yrpC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE26810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCACTTCTCACGCTTTCT, downstream forward: _UP4_TGAATGTAAATGAAAAAGAC
BKK26810 (Δ[gene|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|yrpC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK26810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCACTTCTCACGCTTTCT, downstream forward: _UP4_TGAATGTAAATGAAAAAGAC
References
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Time of last update: 2024-10-10 08:06:47
Author of last update: Melvin.boenninger