ycnD
168
NADPH-FMN oxidoreductase, delivers reduced FMN to enzymes that require the reduced cofactor for activity
locus
BSU_03860
Molecular weight
27.72 kDa
pI
5.08
function
delivery of FMN to enzymes
product
NADPH-FMN oxidoreductase
essential
no
synonyms
ycnD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0778 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
438,516 → 439,265
The protein
Catalyzed reaction/ biological activity
FMNH2 + NADP+ --> FMN + 2 H+ + NADPH (according to UniProt)
FMNH2 + NAD+ --> FMN + 2 H+ + NADH (according to UniProt)
Protein family
flavin oxidoreductase frp family (with [protein|5B95F7CFEFCB954FCBC11087F030A1D777F34B7A|nfrA], according to UniProt)
[wiki|Cofactors]
FMN or FAD [Pubmed|21635694]
Structure
[PDB|1ZCH]
[AF|P94424]
Expression and Regulation
Operons
genes
[gene|C8B3C93479DC1EF6DAD6FCBEEBAD57817BBAFDDA|ycnE]-[gene|BA6C61C488659D5F1B5237BA817A8A5AC6D0E988|ycnD]
description
[Pubmed|17407181]
regulation
induced by chromanon [Pubmed|17407181]
Biological materials
Mutant
MGNA-C013 (ycnD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2011 NBRP B. subtilis, Japan]
BKE03860 (Δ[gene|BA6C61C488659D5F1B5237BA817A8A5AC6D0E988|ycnD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAGACACCCTTCCTT, downstream forward: _UP4_TAAGCTCTTATTCGGCCTGT
BKK03860 (Δ[gene|BA6C61C488659D5F1B5237BA817A8A5AC6D0E988|ycnD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAGACACCCTTCCTT, downstream forward: _UP4_TAAGCTCTTATTCGGCCTGT
References
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Time of last update: 2025-05-02 09:26:35
Author of last update: Melvin.boenninger