ycnD

ycnD
168

NADPH-FMN oxidoreductase, delivers reduced FMN to enzymes that require the reduced cofactor for activity

Locus
BSU_03860
Molecular weight
27.72 kDa
Isoelectric point
5.08
Protein length
249 aaSequenceBlast
Gene length
750 bpSequenceBlast
Function
delivery of FMN to enzymes
Product
NADPH-FMN oxidoreductase
Essential
no
Synonyms
ycnD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0778 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
438,516 → 439,265
The protein
Catalyzed reaction/ biological activity
FMNH2 + NADP+ --> FMN + 2 H+ + NADPH (according to UniProt)
FMNH2 + NAD+ --> FMN + 2 H+ + NADH (according to UniProt)
Protein family
flavin oxidoreductase frp family (with NfrA, according to UniProt)
Cofactors
FMN or FAD PubMed
Structure
1ZCH (PDB)
P94424 (AlphaFold)
Expression and Regulation
Operons
Genes
ycnE-ycnD
Description
PubMed
Regulation
induced by chromanon PubMed
Open in new tab

ycnE→ycnD

2025-03-13 09:17:32

ghost

84

e9d4126e92ae935ad269e47c6892f92b05cdcc20

1D242F7913BFE3D4943FA50E6CCDD71912D63817

Biological materials
Mutant
MGNA-C013 (ycnD::erm), available at the NBRP B. subtilis, Japan
BKE03860 (ΔycnD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGAGACACCCTTCCTT,  downstream forward: _UP4_TAAGCTCTTATTCGGCCTGT
BKK03860 (ΔycnD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGAGACACCCTTCCTT,  downstream forward: _UP4_TAAGCTCTTATTCGGCCTGT
References
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Page visits: 2551

Time of last update: 2025-03-16 09:23:04

Author of last update: Melvin.boenninger