yerC
168
similar to HisR repressor of S. aureus
locus
BSU_06580
Molecular weight
11.89 kDa
pI
4.85
function
unknown
product
unknown
essential
no
synonyms
yerC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4496 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
716,431 → 716,745
Phenotypes of a mutant
inactivation of [gene|B948BD67148DC53B371E6748347982067CE28C36|yerC] reduces sporulation efficiency to 10% that of wild type cells [Pubmed|26735940]
The protein
Structure
[PDB|3KOR] (Trp repressor of Staphylococcus aureus, 67% identity)
[AF|Q7BVT7]
Expression and Regulation
Operons
genes
[gene|BE1F7BA77CE8B6A1A2D22F31421C27F2E954816A|yerB]-[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]
description
[pubmed|22383849]
regulation
expressed under conditions that trigger sporulation ([wiki|Spo0A]) [Pubmed|14651647]
regulatory mechanism
[protein|2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A]: activation, [Pubmed|14651647], in [regulon|protein:2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A regulon]
genes
[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]-[gene|BE1F7BA77CE8B6A1A2D22F31421C27F2E954816A|yerB]-[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-A924 (yerC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/924 NBRP B. subtilis, Japan]
BKE06580 (Δ[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GCGTAATTTATCGATTTGCA, downstream forward: _UP4_TAAAAAACCGCCCTGCCGTC
BKK06580 (Δ[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GCGTAATTTATCGATTTGCA, downstream forward: _UP4_TAAAAAACCGCCCTGCCGTC
References
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Time of last update: 2025-03-17 05:36:39
Author of last update: Jstuelk