catD

catD
168

essential for viability in the presence of catechol

locus
BSU_08230
Molecular weight
14.28 kDa
pI
10.11
Protein length
Gene length
function
detoxification of catechol
product
unknown
essential
no
synonyms
catD, yfiD

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2259 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
897,588 → 897,992
Phenotypes of a mutant
not viable in the presence of catechol [pubmed|30377275]
The protein
Protein family
DoxX family (with [protein|B4384C8C0874BAA7822E9B6DCAB57790018271D8|mhqP], according to UniProt)
Structure
[AF|P54720]
[wiki|Localization]
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|B7A0D1B3CAA2733A33BCCDDB6774ABF1A0223473|catD]-[gene|AA75013C05E1A88FC51410F9F1B30EE7D15F34C2|catE]
description
[Pubmed|16872404]
regulation
strong induction by diamide and quinones (such as catechol) ([protein|73AFDF65BE89C0E2CC59AF2AF64C29BD99D785DF|yodB], [protein|5B9C4932B2E76D6B8F6BDB640D1ADEE28F488FAD|catR]) [Pubmed|16872404,20639328]
induced by iron starvation ([protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]) [pubmed|30377275]
regulatory mechanism
[protein|73AFDF65BE89C0E2CC59AF2AF64C29BD99D785DF|yodB]: repression, [Pubmed|20639328], in [regulon|protein:73AFDF65BE89C0E2CC59AF2AF64C29BD99D785DF|yodB regulon]
[protein|5B9C4932B2E76D6B8F6BDB640D1ADEE28F488FAD|catR]: repression, [Pubmed|20639328], in [regulon|protein:5B9C4932B2E76D6B8F6BDB640D1ADEE28F488FAD|catR regulon]
[protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]: repression, [pubmed|30377275], in [regulon|protein:F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|20639328], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|B7A0D1B3CAA2733A33BCCDDB6774ABF1A0223473|catD]→[gene|AA75013C05E1A88FC51410F9F1B30EE7D15F34C2|catE]

2024-09-25 15:12:14

Jstuelk

53

917958761b4b1f416996a2a063990c7a6fd008bc

2DEC0ECC579FFD7C687FEF51E93AD14225EB14B4

Biological materials
Mutant
MGNA-C294 (yfiD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2292 NBRP B. subtilis, Japan]
BKE08230 (Δ[gene|B7A0D1B3CAA2733A33BCCDDB6774ABF1A0223473|catD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08230 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTATCCTCCTTGATAA,  downstream forward: _UP4_GCATAAGAAAAGAGGCATGC
BKK08230 (Δ[gene|B7A0D1B3CAA2733A33BCCDDB6774ABF1A0223473|catD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08230 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTATCCTCCTTGATAA,  downstream forward: _UP4_GCATAAGAAAAGAGGCATGC
References
17407181,16872404,20639328,30377275

B7A0D1B3CAA2733A33BCCDDB6774ABF1A0223473

Page visits: 6090

Time of last update: 2024-10-06 21:57:44

Author of last update: Melvin.boenninger